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Carbopol 940 polymer is a cross-linked polyacrylate polymer. It is an extremely efficient rheology modifier capable of providing high viscosity and forms sparkling clear water or hydroalcoholic gels and creams.

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Carbopol 940 Polymer. Viscosity, mPas. Carbopol 980 Polymer 15,000. 10,000. Carbopol Ultrez 10 Polymer Carbopol Ultrez 21 Polymer Carbopol Ultrez 20 Polymer. 5,000. 0 0.10% 0.30% 0.50%. Polymer Concentration, wt% TS 4 Neutralization of Carbopol Polymers in Hand Sanitizing Gels The key to formulating a hydroalcoholic gel with Carbopol polymers ...

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The polymers namely Carbopol-934, Carbopol-940, Hydroxypropyl methyl cellulose and Sodium carboxy methyl cellulose were used for formulation of gels and studied for their drug release from the gel formulations. It is evidence from the IR spectrum that all the polymers used in the gel formulations were compatible with the drug Acyclovir.

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Carbomer 940 used for topical formulations and suitable for preparation of gels, creams and coupling agent. Carbomer 380 and cross-linked acrylic resin as well as series products of these cross-linked polyacrylic acid are widely used at present and are often used in topical lotion, cream and gel.

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For local applications are commonly used gels of Carbopol 940 with concentrations from 0.5 to 2% (HORSMEYER & al.). Carbopol is a synthetic carboxyvinylic polymer, which has the advantage of being more uniform, more stable, and more resistant to microbial invasions and growth of fungi due to its high viscosity, even at low concentrations.

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In situ gels with Carbopol ® 940 demonstrated higher viscosity compared to Carbopol ® 934 and drug release was sustained over a period of 8 h. The selected formulation containing 0.8% w/v Carbopol ® 940 and 1.5% w/v HPMC E4M passed sterility test and demonstrated similar antimicrobial efficiency compared to commercial product. The volatile oil of Alpinia galanga rhizomes are known active as antibacterial. Three formulation of gels containing of 1 mL of galangal oil were made with variations of carbopol 940 from 0.5% - 2 %. Antiseptic test were done using replica methods. Data of viscosity, spread power, and adhesion were analyzed using one way ANAVA.

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