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AMG-510: This year, results were presented on AMG-510 which showed a high response rate in both lung and colorectal cancers. AMG-510 targets a KRAS mutation also known as KRAS G12C, which occurs in approximately 3-5% of colon and rectal cancers.

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Download presentations members of our team have given at recent conferences and meetings. Vosaroxin Program Presentations and from Investigator Sponsored Trials. Publications. Download reprints of research and studies which have submitted to scientific and medical journals. Vosaroxin Program Publications. Most Recent Presentations - Sunesis Trials

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James Frame, M.D., FACP, Medical Director, David Lee Cancer Center, Chair ASCO REMS Working Group, President, West Virginia Oncology Society 3:45 p.m. – 4:30 p.m. Opioid REMS and What It Signals For the Future of REMS

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INDIANAPOLIS, May 18, 2016 /PRNewswire/ -- Several studies will underscore the strength of Eli Lilly and Company's (NYSE: LLY) diverse clinical cancer pipeline and portfolio during the 52 nd Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, June 3 - 7, 2016. Presentations include new data on abemaciclib, a CDK 4 and ... Jun 01, 2020 · Shots: The CodeBreaK 100 development program evaluates AMG 510 (proposed INN sotorasib, qd) in heavily pretreated patients with a range of KRAS G12C-mutant solid tumors. Eligible patients were heavily pretreated with at least 2L+ treatment and were enrolled four dose cohorts: 180 mg/360 mg/720 mg/960 mg This Phase 1 dose-escalation study evaluated 42 heavily pretreated […]

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Von Minckwitz G, et al ASCO 2013, Abstract # 1004 + Bevacizumab + Platinum. ... AMG 386. Vascular Disruptor. Amgen. October 2011. AMG 479 + Metformin. IGFR Inhibitor ...

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Aug 04, 2019 · Furthermore, not only was the primary end point met, but AMG 510 showed impressive results with regard to the 50% response rate and the disease control rate of 90% (9 out of 10 patients, with five ... May 29, 2020 · THOUSAND OAKS, Calif., May 29, 2020 /PRNewswire/-- Amgen (NASDAQ:AMGN) today announced new data from the CodeBreaK 100 clinical development program evaluating investigational AMG 510 (proposed INN sotorasib) in heavily pretreated patients with a range of KRAS G12C-mutant solid tumors.

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